SYRINGOCYSTADENOMA PAPILLIFERUM
Papillary processes having connective tissue cores that often contain plasma cells usually communicate with the skin surface in syringocystadenoma papilliferum. The connection may be via follicular infundibula recapitulating the connection of the embryological apocrine unit with the hair follicle. These occur most frequently on the scalp but can occur elsewhere. These are sometimes found in the background of  nevus sebaceus of Jadassohn. The classical description emphasizes a double layer of epithelium lining the papillary surfaces with a columnar layer on the luminal side and a cuboidal layer on the other. Epithelium that appears to be more piled up is seen more frequently.

The papillary hyperplasia that is seen in some examples of apocrine tubular adenoma is usually devoid of the connective tissue cores of the type seen in syringocystadenoma papilliferum.

Hidradenoma papilliferum usually does not communicate with the surface as broadly or at all, and is found almost exclusively in the pudendal region of females.


 
Scan showing multiple papillary structures beneath a defect in the epidermis.
Low power showing connection with squamous epithelium that could be of follicular infundibulum type. Taken from left side of scanning view.
High power showing connective tissue core containing plasma cells in a papillary process..

Click on your browser's 'Back' button to go to previous page.