SPINDLE CELL LIPOMA
This benign tumor occurs most frequently in adult male patients and is most often located in the regions of the posterior shoulder and neck. Mature birefringent collagen bundles, mature adipose tissue, relatively uniform spindle cells, and, usually, myxoid foci are present in the prototypic case. The relative proportion of each of these constituents varies considerably from case to case and may be variably prominent within a given tumor. Mast cells are commonly present. Cytologic atypia is seen in some cases and this raises the possibility of spindle cells lipomas being related to pleomorphic lipomas.

This mass was easily removed from the subcutaneous tissue from the posterior aspect of the lower neck of an adult male. The surgeon's postoperative diagnosis was lipoma.
 
 
Direct scan view of two cross-sections of the tumor. Note the variation in density from area to area. 
A low power view from an area of moderate density showing a combination of mature fat, mature collagen, and a moderately cellular component. Many of the uniform spindle cells are oriented parallel to each other. Tissue mucin is barely visible at this magnification.
Medium power view  mature fat, collagen, spindle cells, and tissue mucin.
High power view showing a few spindle cells, mast cells (MC), and mature collagen.
Low power view of a less cellular area that is. composed of mature adipose tissue, collagen, and a few spindle cells. 
Medium power view of above. Very little tissue mucin is seen in this area. Some of the spindle cells are oriented in a parallel pattern.

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