INTRADUCTAL NIPPLE DUCT ADENOMATOSIS
This lesion of the nipple was translucent and had an estimated diameter of 4 millimeters clinically. Clear fluid could occasionally be expressed from the nipple. The patient is 71 years old.

This could be interpreted as a variant of nipple duct adenomatosis or it could be interpreted as an intraductal papilloma involving a nipple duct. There are papillary structures having connective tissue cores, and, additionally, there are naked fronds of epithelium protruding into lumina. This particular lesion appears to be confined to the duct lumen rather than being a papillary proliferative process within the stroma of the nipple as might be the case in classical nipple duct adenomatosis. The important point is that this lesion is benign.
 
 
Scan power view. The nipple surface is at the top of the picture. There is squamous metaplasia of a markedly dilated nipple duct in the deep aspect of the dermis, and the intraductal papillary lesion is below this surface.
Medium power view. Naked fronds of epithelium have a papillary pattern within lumina.
Another medium power view. These papillary processes have connective tissue cores.

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