This type of lesion classically occurs on hands or feet and is characterized by replacement of the epidermal surface cells my mucin containing epithelium that does not keratinize. Mucinous metaplasia can be seen in other settings including clear cell hidradenomas (acrospiromas) and other adnexal tumors. Mucinous metaplasia can occur in eccrine or apocrine epithelium.
 
 

	Scan power view of a lesion of the hand of an adult carpenter. The mucinous secretions made his hammer slip in his hand, so he sought medical attention. Excision was curative. Note the lack of keratin production over the lesion.
	High power view of an H&E stained section. Goblet cells (GC) are noted.
	Low power view, mucicarmine stain. The number of involved epidermal surfaces exceeds the normal number of eccrine ducts in this region, so there must be surface proliferation of these cells.
	High power view, mucicarmine stain. The mucus is red.

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