Nevus cells were found in 5 of the 42 cases originally reported as
fibrous papule of the nose by Graham et al. They concluded that fibrous
papules of the nose represented regressed nevi. Subsequently, there have
been several theories as to the histogenesis of this common, benign lesion.
The most attractive is that these are fibromas of follicular fibrous sheath
origin with variable expression of follicular epithelial elementssee
Reed. In view of the occasional association of nevus cells with
follicular
malformations, hamartomas, and
desmoplastic
trichoepitheliomas, it is not surprising that nevus cells would be
found in some fibrous papules. Many of the features of fibrous papule
of the nose are presented elsewhere.
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Scan power view. The papular nature of the lesion is apparent. |
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Composite low power view. |
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A medium power view from the upper center of the picture above. Nevus cells are found close to the center of the picture. Prominent blood vessels with perivascular fibrosis plus plump fibrohistiocytic cells are seen. |
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High power view illustrating the features mentioned above.. |
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Medium power view from another area. Parallel, coarse collagen fibers are oriented perpendicular to the dermoepidermal interface. This is very characteristic of fibrous papules. |
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Medium power view from the base of the specimen. Hypertrophy of the fibrous follicular sheath is associated with two follicular figures, one of which has anagen phase features and the other has catagen or telogen phase features. |
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