The fibrous follicular sheath component of this hamartoma is prominent. Sebaceous units are dominant in this example, and there is a suggestion of cyst formation in the scan power view. Deeper sections demonstrated a connection with the epidermis.
This tumor and related tumors are mentioned in the discussion of
perifollicular fibromas.
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Scan power view. The arrows mark the interface of the tumor (lower left) and the reticular dermis (upper right). |
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Low power view of above. Note the difference between the reticular dermis collagen pattern (above and right of the arrows) and the tumor stroma (below and left of the arrows). |
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High power veiw from the interior of the tumor. The collagen fibers are coarse and intersect the epithelium in a perpendicular fashion similar to that found in fibrous papules of the nose and in other fibroepithelial folliculosebaceous hamartomas. |
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Another scan power view from a deeper section that shows an area of connection with the epidermal surface. |
Reference:
1. Kimura et al. Folliculosebaceous cystic hamartoma. A distinctive
malformation of the skin. Am J.Dermatopathol. 1991 Jun;13(3):213-20.
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