NEVUS SEBACEUS OF JADASSOHN OF THE FACE
This oval lesion from the face of a 21 year old patient became noticeable during puberty, and it developed a rough surface.

Nevus sebaceus of Jadassohn represents a focus of defective embryogenesis of pilosebaceous units, including the apocrine component. Subsequently, and frequently at the time of puberty, various components of the pilosebaceous unit may proliferate. Multiple combinations and permutations occur. The lesion is more easily diagnosed pathologically on the scalp (the most frequent site) since it is easier to recognize defective formation of large anagen phase follicles in that location than it is to recognize malformations of pilosebaceous units on the face.

Round, facial papules that occur in adults that are composed of prominent sebaceous units usually represent adenoid sebaceous hyperplasia. The history of this being an oval or linear lesion becoming apparent during puberty is more consistent with nevus sebaceus of Jadassohn. The overlying epidermal hyperplasia resembling a seborrheic keratosis is a common feature of nevus sebaceus of Jadassohn. The epidermal lesion could also be designated as an epidermal nevus (hamartoma).
 
 
 
 
Scan power view. The central sebaceous units are abnormally prominent. The epidermal component is most prominent on the 'left' side of the lesion.
Low power view of the epidermal part of the lesion. This could be construed as hyperplasia of follicular infundibular epithelium.

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