This is a sharply circumsribed tumor that is characterized by stacked lamellae of eosinophilic collagen that are associated with widely scattered cells that resemble fibroblasts or cells of the perineurium. In addition to the stacked pattern of parallel collagenous lamellae, some have starburst or storiform patterns. Some of these have myxoid matrix, but the matrix is clear in others. Foci resembling this tumor can uncommonly be found in cutaneous neurofibromas. Occasional dermatofibromas contain a zone that is cell-poor, and such foci may vaguely resemble the starburst pattern found in fibrolamellar nerve sheath tumors.
| Scan view | |
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Low power, right edge. Normal dermis a little to the right of the sweat duct. Note sharp line of dermarcation between tumor and dermis.. |
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High power showing stacked lamellae of collagen. |
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High power showing a starburst or storiform figure composed mostly of collagen. |