ECCRINE POROMA WITH SYRINGOFIBROADENOMATOUS PATTERN
Eccrine syringofibroadenoma (Mascaro) is a lesion that is most commonly found on the lower extremity of an elderly person. It is not surprising that the interlacing delicate strands of epithelium that are characteristic of eccrine syringofibroadenoma could occur in the background of an acrosyringeal tumor having other features of eccrine poroma.  There are simulants that probably are reactive and these have been associated with a variety of conditions including ulcers, chronic lymphedema, and pemphigoid. 

From the leg of an adult:
 
Direct scan of the glass slide.
Low power view of the area in the black rectangle above. Interlacing strands of small uniform cells of acrosyringeal type are separated by vascular connective tissue.
Scan power view from another section.
Low power view of the area in the black rectangle above. Bulbous acanthosis of monotonous small epithelial cells of acrosyringeal type are present and are characteristic of eccrine poroma.
High power view from the area in the red rectangle seen in the scan power view. There is a focus of prominent duct differentiation.

Click on your browser's 'Back' button to return to the previous page.