ECCRINE SPIRADENOMA
Spiradenomas are composed of small cells that, for the most part, do not have visible cytoplasmic junctions. Some of the nuclei stain more deeply than others resulting in the light and dark cells mentioned in the texts. Similar cells may be seen in cylindromas. The tumor nests in spiradenomas are larger and have rounded outlines in contrast with the smaller, more angulated outlines seen in cylindromas. The interiors of tumor nests in spiradenomas frequently are quite vascular. There may be glassy eosinophilic material deposited in the interiors of tumor nests, and this material frequently is associated with blood vessels. Less frequently, such material may be seen around the periphery of  a tumor lobule. There are 'hybrid' tumors having combined features of spiradenoma and cylindroma. Duct differentiation and/or intracytoplasmic lumen formation usually are minimal or absent in spiradenomas.

 
Spiradenoma composed of light and dark cells having no visible cytoplasmic junctions.
Low power view of a spiradenoma having more duct formation and intracytoplasmic lumen formation than usual.
High power view of above

Click on your browser's 'Back' button to return to the previous page.