dermatofibroma containing osteoclast-like giant cells

DERMATOFIBROMA CONTAINING OSTEOCLAST-LIKE GIANT CELLS

Osteoclast-like giant cells are uncommon in dermatofibromas though they have been reported. Ostoclast-like giant cells are seen more commonly in giant cell tumors of tendon sheath origin and in peripheral giant cell granulomas (gingiva). Such giant cells contain numerous, crowded nuclei, and the cytoplasm of such cells stains more darkly than other cells in the adjacent tissue.

This example is from a 19 year old male.

Scan power view. This specimen was received in a fragmented state.

Medium power view. The osteoclast-like giant cells are prominent in the background of an otherwise ordinary dermatofibroma.

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	Scan power view. This specimen was received in a fragmented state.
	Medium power view. The osteoclast-like giant cells are prominent in the background of an otherwise ordinary dermatofibroma.