BLUE NEVUS HAVING STROMA THAT IS VERY DESMOPLASTIC
Desmoplasia is a property of some nevi, and this is particularly true of  blue nevi. The dispersed distribution of  spindle shaped melanocytes between variably dense collagen bundles is characteristic of the common blue nevus. 

It is interesting that the lesion that has been designated desmoplastic nevus is thought to be related to spindle and/or epithelioid cell nevi (Spitz). That is probably because spindle and/or epithelioid cell nevi  constituted the group of lesions under study when desmoplasia was noted. In reality, blue nevi would have better deserved the title.


A very firm, pigmented, clinically indolent lesion from a 39 year old male:
 
Composite scan power view. A melanocytic epidermal component is not present. The increased density of the lesion (upper left reticular dermis) when compared to the remainder of the reticular dermis is very apparent in this picture. Most of the pigmented spindle cells are in the right side of the lesion.
Medium power view from the middle of the lesion. Note the density of the collagen. The pigment is melanin.
Medium power view of the junction of the lesion (top of the picture) and the  uninvolved reticular dermis (below). Compare the density of the collagen.

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