clear cell hidradenoma variant of acrospiroma

CLEAR CELL HIDRADENOMA TYPE

OF ACROSPIROMA

A discussion of the acrospiroma terminology is presented elsewhere. Suffice it to say, the lesion referred to by some as clear cell hidradenoma is solidly entrenched as a type of acrospiroma. Such lesions are considered by many to be eccrine, but apocrine differentiation is occasionally seen in clear cell hidradenomas.

This particular example communicates with the epidermis, but, as is true of the other tumors that are in the acrospiroma group (dermal duct tumors and poromas), there are examples restricted to the dermis in addition to those that communicate with the epidermis. The epithelial cells in the clear cell hidradenomas are usually larger than those found in the other acrospiromas, and the stroma contains delicate blood vessels. The epithelial cells may radiate from these delicate blood vessels. Mucus production is seen in a few, and cuboidal or columnar luminal differentiation or modulation is found in some examples. Clear cells are not necessarily present, and such cases are best diagnosed as 'acrospiroma' based upon other criteria including the relationship of the tumor cells to blood vessels.

Scan power view. Note the epidermal connection/s.

A high power view. Cuboidal and low columar cells form lumina in this example. There are two delicate blood vessels in this picture. Clear cell differentiation is seen, and the cells are larger than those found in the other acrospiromas.

Another high power view. The luminal cells have some apocrine features. A few delicate blood vessels are in this picture. Some of the epithelial cells have clear cytoplasm and some do not.

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	Scan power view. Note the epidermal connection/s.
	A high power view. Cuboidal and low columar cells form lumina in this example. There are two delicate blood vessels in this picture. Clear cell differentiation is seen, and the cells are larger than those found in the other acrospiromas.
	Another high power view. The luminal cells have some apocrine features. A few delicate blood vessels are in this picture. Some of the epithelial cells have clear cytoplasm and some do not.