APOCRINE TUBULAR ADENOMA (WITH VERRUCOID ARCHITECTURE)
Apocrine tubular adenomas share some features with syringocystadenoma papilliferum. Verrucoid architecture is common in syringocystadenoma papilliferum, but the papillary processes in that lesion have connective tissue cores. The connective tissue cores frequently contain plasma cells in syringocystadenoma papilliferum.
Intraluminal papillary hyperplasia can occur in apocrine tubular adenomas, but this consists of intraluminal budding or bridging without the formation of connective tissue cores. Intraluminal cellular detritus is more common in apocrine tubular adenomas. The verrucoid hyperplasia in either lesion may be thought of as hyperplasia of follicular infundibular epithelium into which the apocrine gland normally inserts embryologically.

 
Scan of lesion from chin demonstrating verrucoid architecture of a lesion containing tubular elements.
Low power view showing a tubular structure inserting into the surface epithelium. This could be interpreted as follicular infundibulum.
High power of above. Note the prominent granular layer. Follicular infundibular epithelium on the face may have a prominent granular layer. This doesn't necessarily  indicate wart virus infection.
Low power view showing intraluminal cellular proliferation without connective tissue core formation. Some cellular detritus is present.
High power view of bridging type of intraluminal hyperplasia.
High power view of intraluminal cellular detritus.

Click on your browser's "Back" button to go to previous page.