ANGIOLIPOMA
Angiolipomas are benign tumors of the subcutis that may be painful or tender and are encountered most frequently in young adults. Such tumors are composed of mature fat within which varying numbers of small blood vessels are present. Pain and/or tenderness are independent of the number of small vessels. Myxoid foci and collagenous tissue are less common than in spindle cell lipomas, but there are examples of spindle cell lipoma that may be quite vascular. Fibrin thrombi, which are almost invariably present in angiolipomas, are typically not present in spindle cell lipomas.

A tender mass from the arm of an adult male:
 
Scan power view. Note the regional variation in the density of the lesion.
A medium power view. Numerous vessels of capillary dimension are associated with mature adipose tissue.
Another medium power view. There is a myxoid focus in the center of this area, and there are mast cells within it.
A high power view showing fibrin thrombi (FT).

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